Experimental study on inducement of rat small bowel trans-plantation tolerance by immature dendritic cell cultivated and expansed in vitro / 中国现代普通外科进展
Chinese Journal of Current Advances in General Surgery
;
(4)1998.
Artigo
em Chinês
| WPRIM
| ID: wpr-547078
ABSTRACT
Objective:
To discuss the feasibility of immune tolerance in rat small bowel trans-plantation induced by immature dendritic cells isolated from SD and Wistar rat.Methods:
Dendritic cells isolated from liver or bone marrow of inbred strain Wistar and SD rat were cultured for five to nine days. A week before operation, the recipient rats were injected 2?106 inmature DCs from vena dorsalis penis and observed. The models of heterotopic small bowel transplantation (SBT SD→ Wistar)were established. Acute immuno- rejection levels were evaluated by HE.Results:
Varying degrees of rejection were observed in 3, 5, 7 days after operation.Conclusion:
Immature DC can induce allogenic immunological tolerance of rat small bowel transplantation.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Current Advances in General Surgery
Ano de publicação:
1998
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS