Effect of SU11248 on proliferation and apoptosis of myeloma cell line U266 / 中国免疫学杂志
Chinese Journal of Immunology
;
(12)1986.
Artigo
em Chinês
| WPRIM
| ID: wpr-547441
ABSTRACT
Objective:
To investigate the effect of SU11248 proliferation and apoptosis of multiple myeloma cell line U266 in vitro and analyze its mechanisms.Methods:
Effect of SU11248 on proliferation of U266 cells was detected by MTT assay.The ability of SU11248 to induce apoptosis of U266 cells was examined by cell cycle analysis,TUNEL and DNA fragmentation.Expression of c-myc,hTERT,Bcl-2 and Bax mRNA in U266 cells was assessed by RT-PCR analysis.Results:
The proliferation of U266 cells was inhibited by SU11248 in dose-and time-dependent manners (P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Immunology
Ano de publicação:
1986
Tipo de documento:
Artigo
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