Influence of Cardiopulmonary Bypass on Plasma Digoxin Concentrations / 第二军医大学学报

ABSTRACT

Plasma digoxin concentrations were measured by radioimmunoassay in 34 patients undergoing cardiac valve replacement before and after cardiopulmonary bypass. The concentration before the start of the bypass was 1. 379?0. 760 ng/ml while that after completion of the bypass was 0. 812?0. 529 ng/ ml with an average reduction of 0. 634?0. 481 ng/ml. The difference was remarkable (P