Study on the pathology shape structure of calcified cartiage zone in osteoarthritis knee joint / 中国矫形外科杂志

ABSTRACT

[Objective]Study on the Pathology shape structure of calcified cartilage one in Osteoarthritis knee joint and provide the theory for diagnosis and treatment of correlated disease.[Method]Osteoarthritis condyles of femur(n=21) were collected from knee joint replacement and the paraffin sections were prepared after fixation and decalcification.After stained with Safranin O/fast green,the shape structure of calcified cartilage zone was observed by microscope.[Result]Mean age of osteoarthritis patient was 65.57?7.43 yearsold;mean stature was(155.38+5.32)cm;mean weight was(59.95 ?8.99)kg;mean pathogenesis was(13.04?9.66) years.After stained with Safranin O/fast green,the pathological changes of calcified cartilage zone were defined as follow.Tidemark drift and thickening accompany with blood vessel invasion.The gap of tidemark increased width.Calcified cartilage zone desmoid changed or defect.[Conclusion]Calcified cartilage zone in Osteoarthritis knee joint taken place specific pathological changes.