Dynamic changes of nitric oxide and prostaglandine levels in gastric mucosa and plasma in rats with seawater immersion after open abdominal trauma / 中国现代普通外科进展

ABSTRACT

Objective:To explore the dynamic changes of nitric oxide and prostaglandine levels in gastric mucosa and plasma of rats with seawater immersion injury after open abdominal trauma Methods:Thirty-two Sprage-Dawley rats were randomly assigned into four groups:normal control group,celiac seawater-immersing trauma stress 1,2,3h groups.The contents of nitric oxide and prostaglandine in gastric mucosa and plasma of rats were detected by chemochromometric and immunoassay methods respectively.Results:Compared with normal control group,both the nitric oxide and prostaglandine levels in gastric mucosa and plasma of rats under celiac seawater-immersing trauma were progressively increased (P