Renal Toxicity Induced by Melamine Intake Single and Combined with Cyanuric Acid / 环境与健康杂志
Journal of Environment and Health
;
(12)2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-548077
ABSTRACT
Objective To explore the renal toxicity induced by melamine intake single and combined with cyanuric acid.Methods Thirty-six clean weanling male Wister rats were randomly divided into 3 groups,12 in each,treated with melamine and cyanuric acid through food for 28 consecutive days,group 1 treated with melamine at 25 mg/kg,group 2 treated with melamine (25 mg/kg) plus cyanuric acid (25 mg/kg),group 3 is control,fed on normal pet food.After 4 weeks of treatment,the rats were sacrificed and blood indicators,histopathological examination of kidney were conducted.Renal tissues from the affected rats were analyzed using high-performance liquid chromatography and mass spectrometry.Kidney X-ray diffraction was performed to determine the existence of crystals.Results In group 1 and 2,polyuria,hypokinesia and weight loss (P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Environment and Health
Ano de publicação:
2007
Tipo de documento:
Artigo
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