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PHARMACOLOGICAL INVESTIGATION ON"FU-TZE" (A CHINESE HERBAL MEDICINE) V. THE EFFECTS OF ACONITE ROOT ON A PATHOLOGICAL MODEL TERMED "THE PULSE SCARCELY FELT / 第二军医大学学报
Academic Journal of Second Military Medical University ; (12)1982.
Artigo em Chinês | WPRIM | ID: wpr-548900
ABSTRACT
Observations on blood pressure and myocardial contraction were taken on 20 cats under urethane anesthesia and artificial respiration. 3% sodium pentobarbital solution was injected intravenously into the cats until the blood pressure dropped to about 10 mm Hg, the heart beat nearly arrested and the pulsation scarcely felt, then, the boiled extract of aconite root equivalent to dried herb 100-400 mg/kg was injected intravenously, the response of the cats were striking, the blood pressure rose markedly, and the amplitude of myocardial contraction significantly enhanced. Same results were obtained when the experiments were repeated.By pharmacological analysis it is more likely that the pressor effect is due to the stimulation action on the ?-receptor of the vascular wall and the cardio-tonic effect is in connection with ?1-receptor of the myocardium.
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Academic Journal of Second Military Medical University Ano de publicação: 1982 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Academic Journal of Second Military Medical University Ano de publicação: 1982 Tipo de documento: Artigo