EFFECTS OF INTERFERON ON MITOMYCIN-INDUCED SISTER CHROMATID EXCHANGES AND ON ULTRAVIOLET-LIGHT-INDUCED UNSCHEDULED DNA SYNE THESIS / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12)1985.
Artigo
em Chinês
| WPRIM
| ID: wpr-549373
ABSTRACT
We studied the effects of interferon(IFN) on sister chromatid exchanges(SCE) induced by mitomycin(MMC) and/or on unscheduled DNA synthesis(UDS ) induced by ultraviolet light(UV) in peripheral lymphocytes taken from 4 normal individuals and 3 patients with xeroderma pigmentosum(XP) in whom the existence of congenital DNA excision repair defect had been verified.The lymphocytes from 2 normal individuals and 3 patients with XP were treated with IFN 8 hours before MMC was added SCE frequencies in IFN groups were lower than those in the controls. Statistical computation showed that all differences were highiy significant(P0.05).
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Academic Journal of Second Military Medical University
Ano de publicação:
1985
Tipo de documento:
Artigo
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