An Approach to Clinical and Pathological Classification of Chronic Active Hepatitis / 第三军医大学学报

ABSTRACT

The clinical and pathological data of 208 cases of chronic active hepatitis (CAH) were analyzed, pre liminarily. CAH can be categorized into 6 clinical types (1) anicteric type, (2) icteric type,(3) severe jaundice and ascites type, ( 4 ) advanced cirrhrotic type, ( 5 ) obstructive jaundice type, and ( 6 ) atypical type.The pathological findings of the 208 cases can be divided into the following. (1) periportal necrotico-inf lammatory type, in which piecemeal necrosis(PN) was prominant, ( 2 ) bridging necrotic type, in which PN and bridging necrosis were present, ( 3 ) submassive necrotic type, multilobular or submassive necrosis occurred, ( 4 ) hepatitis-cirrhotic type, PN with fibrous septa and formation of pseudolobules were seen, and ( 5 ) cholestatic type, PN with intrahepatic cholestasis was pathognomonic.