Hemodynarnic Changes after Superior Mesenteric Artery Occlusion in Dogs / 第三军医大学学报

ABSTRACT

In order to study the characteristics of the early cardiovascular responses following the occlusion of the superior mesenteric artery, occlusion of the artery was perfomed on 7 dogs, and sham operation on 6 dogs to serve as control- It was found that after the release of the occlusion 2 hours later, the mean arterial pressure and the central venous pressure of the experimental group dropped significantly. Comparable changes could not be observed in the controls. Meanwhile, the parameters of left ventricular functions such as left ventricular systolic pressure, + dp/dt max, = dp/dt max, Q-dp/dt max interval, and the product of 3 items(cardiac rate, Q-dp/d max interval and the peak value of left ventricular pressuure) showed no difference between the 2 groups.The results suggest that the general functional derangement of the cardiovascular system can be ascribed to the pooling of blood and/or fluid in the splanchnic area, and the adnormal myocardial performance does not appear in the initial phase of superior mesentric artery occlusion.