Effects of Physical Activity on Cardiopulmonary Hemodynamics in Hypoxic Conscious Goats / 第三军医大学学报

ABSTRACT

The effects of physical activity on cardiopulmonary hemodynamics under acute hypoxia at a simulated altitude of 4000 meters were studied in 8 conscious goats. It is known that acute hypoxia alone can result in an elevation of pulmonary arterial pressure and acceleration of heart rate, but no obvious effects on cardiac output and systemic arterial pressure, and physical activity can increase the pulmonary arterial pressure, cardiac output and heart rate at sea level. It was found that a combination of physical activity and a simulated altitude of 4000m could bring about a more marked increase of cardiac output and heart rate but no further increase of pulmonary arterial pressure. The latter phenomenon might be due to increased alkalinity of the arterial blood underhypoxic condition.