THE OBSERVATION ON THE MORPHOLOGY AND MORPHOGENESIS OF ROTA-VIRUS BY ELECTRON MICROSCOPY / 解放军医学杂志

ABSTRACT

On the basis of electron microscopic examinations of 52 specimens of faeces collected from patients with acute nonbacterial diarrhea, three standard strains of rotavirus were adapted to LLC-MK2 cell line. The results showed that morphology and structure of rotavirus particles were similar. The cytoplasmic inclusion body could be seen in the infected cells. The viral particles could be found in the nuclear membrane space, cisterns of the rough endoplasm reticulum and the inclusion body