STUDY ON HYPOTENSIVE CONSTITUENT OF RHODODENDRON MOLLE ( BI. ) G.DON / 中国药理学通报

ABSTRACT

Four constitunets were isolated from the flower of Rhododendron molle ( BI. ) G. Don. One of these was named Rdl.The acute LD50 of Rdl in mice ( iv ) was found to be 4742 ug/kg.The hypotensive effect of Rdl was studied in various anesthesized animals. In cats, the dosage of 100, 300 and 500 Hg/kg of the Rdl ( iv ) reduced the blood pressure by 109% ( P