The Effects of circadian Rhythm on Tolerance to Acute Hypcxia in Mice / 第三军医大学学报

ABSTRACT

The relationship between circadian rhythm and tolerance to acute hypoxia at a Simula ted altitude of 10000m was studied in 110 micc.Bolh number of survival and surviving time were increased from 3 00 and reached the hightidc at 500.From then the number of survival remained at the same level,the surviving time declined gradually.Both the number of survival and surviving time attained the lowest value at 14 56 to 030.The results suggest 1.there is a close relationship b etween circadian rhythm and tolerance to acutehypoxia; 2.when rodents arc used for this kind of study,the affect of circadian rhythm should be considered.