EFFECTS OF SAPONNINS OF ZIZYPHUS JUJUBA NILL SEEDS ( ZS ) ON PLASMA LIPIDS AND LIPOPROTEINCHOLESTERINS OF RATS / 中国药理学通报

ABSTRACT

The effects of ZS on plasma lipids and lipoprotein-cholesterins of rats fed on normal diet and rats fed on rich-fat diet were studied. It was found that ZS at 64 mg/kg?d-1 ip for 20 d could reduce the levels of TC and LDL-c, increase HDL-c and HDL 2 -c of rats fed on normal diet. ZS at same dosage could reduce TG, and increase HDL2-c of rats fed on rich-fat diet. It was demonstrated by this study that ZS could be of great advantage to protection from as in rats.