Distribution of Hematoporphyrin Monomethyl Ether in Tumor-bearing Mice / 第二军医大学学报

ABSTRACT

spleen(?)heart(?)muscle.The pharmacokinetics of PsD-044 in mice was fitted by an open three compartment model. The pharmacokinetic parameters calculated were shown to be essentially consistent with the determination of tissue distribution. It was also shown that PsD-044 can't pass through blood-brain barrier.