Immunohistocheinical Localization of Copper-Zinc Superoxide Dismutase in Human Hepatocellular Carcinoma and Its Surrounding Tissues / 第二军医大学学报

ABSTRACT

By using protein A-gold labeling probe, copper-zinc superoxide dismutase (Cu-Zn SOD)in paraffin-embedded sections of 24 cases of human hepatocellular carcinoma (HCC) and its surrounding liver tissues was immunolocalizied The experimental results showed that in a good many of HCCs and its surrounding liver tissues, immunostaining of Cu-Zn SOD appeared differently positive, but in 2 cases of grade Ⅱ differentiation, massive pattern of HCC, Cu-Zn SOD immunostaining was negative. In one hepatoma was clear cell carcinoma, and in another one tumor cells followed obvious fatty degenera tioa Two problems that what was significance of Cu-Zn SOD in HCQ and a few cellular nuclei labeled for Cu-Zn SOD are disscussed.