THF TOXICITY OF MALTOL AND ITS EFFECT ON ANTIOXIDATIVE ENZYME ACTIVITIES OF ERYTHROCYTES IN MICE / 中国药理学通报

ABSTRACT

According to our previous experimental results, maltol is a powerful antioxidant against autoxidation and oxidative stress of eryth-rocytes. In this report, the toxicity and antioxidative action of maltol in mice was investigated. The results indicated that maltol was not toxic in mice when fed in a dose of 50mg/kg?d-1 (body weight) for 1 month. The antioxidative enzymes ( SOD and Cat ) activities and GSH content of erythrocytes were significantly increased. In addition, the lifespan of houseflies fed with maltol was prolonged.