Left Ventricular Function Change of Hemorrhagic Shock in the Dog / 第三军医大学学报

ABSTRACT

Left ventricular function change was investigated in dogs during the postin-fusion period of experimental hemorrhagic shock. Hemodynamic parameters and the first derivative of left ventricular pressure (dp/dt) were recorded with an 4-channal polygraph and LVP-dp/dt loop was displayed on an attached oscilloscope simultaneously. In the study, LV function was assessed by + dp/dtmax, dp/dt/DP5.33, VCE at +dp/dtmax, Vmax, - dp/dtmax, - dp/dtmax/LVSP and VCE at -dp/dtmax. The results show that hemodynamic and LV function parameters approximate to the control levels 10 min after reinfusion. The performance then depresses significantly 60 min after renfusion and cardiac function deteriorates soon thereafter. The data are interpreted as direct evidence for a seriously-depressing myocardial performance during the early postin-fusion period of hemorrhagic shock in the dog.