EFFECTS OF TAURINE, QUINIDINE AND THEIR COMBINATION ON EXPERIMENTAL ARRHYTHMIAS INDUCED BY ACONITINE IN MICE / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12)1987.
Artigo
em Chinês
| WPRIM
| ID: wpr-550492
ABSTRACT
The constant iv. of aconitine can induce the varied arrhythmias in mice. Taurine 100mg/kg iv. or Quinidine 5 mg/kg iv. can delays the onset time of arrhythmias, and increases the dose of aconitine, respectively .But no effects were seen in mice pretreated with taurine 50mg/kg or quinidine 2.5mg/kg. However their combination can significantly decrease the incident of ventricular fibrillation and delay the onset time of death. Our results suggested that taurine, quinidine and their combination are effective on arrhythmias induced by aconitine in mice.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmacological Bulletin
Ano de publicação:
1987
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS