THE STUDY ON THE MECHANISMS OF IMMUNOSUPPRESSIVE EFFECT OF TRIPTERYGIUM WILFORDII HOOK ( TWH ) / 中国药理学通报

ABSTRACT

The mechanisms of immunosuppression of TWH were studied. The results indicated that TWH was able to reduce the antibody forming cells of splenocytes in mice and to suppress directly the proliferation of B cells to lipopolysaceharide ( LPS ) and to decrease the production of IL-2. Furthermore, TWH was able to produce immu-nosuppressive effect by activiting Ts cells.