EFFECTS OF SUPERNATANTS FROM CULTURED RAT PINEAL GLANDS ON THE FUNCTIONS OF LYMPHOCYTES / 中国药理学通报

ABSTRACT

Effects of supernatants from cultured rat pineal glands on ConA and LPS induced proliferative responses of splenocytes in mice, ConA induced interleukin 2 (IL-2) production of splenocytes in rats were studied. These results showed that ConA and LPS induced proliferative responses of splenocytes were enhanced by supernatants from cultured rat pineal glands stimulated with 10 ?mol/L isoproterenol (ISO) for 60 min (Dilution. 1 : 45 ) , ConA induced IL-2 production of splenocytes in rats was also enhanced by the supernatants (Dilution: 1 : 135 ) .