Study on volume-pressure relationship during the progression of an acute intracranial space-occupying lesion in dogs / 第三军医大学学报

ABSTRACT

An inflatable liquid epidural balloon was used to simulate an intracranial space-occupying lesion.Two groups of dogs with 8 in each were employed.Under different conditions and time intervals,intracranial pressure(ICP)was continuously recorded,and pressure-volume index(PVI),volume-pressure response(VPR),and cerebrospinal fluid pulse pressure(CSFPP)were measured silmutaneously.It was found that PVI was in significant negative linear correlation with ICP,while VPR and CSFPP in significant positive linear correlation with IVP(P