Changes of plasma TNF level during pseudomonas aeruginosa septicemia in rabbits / 第三军医大学学报

ABSTRACT

It was found that after 2 dosages of Pseudomonas aeruginosa suspension(7?109/kg and 2?1010/kg)were infused to rabbits respectively to induce septicemia,the elevation of the tumor necrosis factor(TNF)level in the circulating blood was higher in 2?1010/kg group than in 7?109/kg group.The dynamic changes of circulation TNF in P.aeruginosa septicemia were different from those in endotoxin shock.There was a continous increase of plasma glucagon,Iactic acid and ?-G(P