Can Carbohydrate-Deficient Transferrin (CDT) Reflect Alcohol Consumption in Korean Male Drinkers?
Journal of the Korean Academy of Family Medicine
;
: 451-455, 2005.
Artigo
em Coreano
| WPRIM
| ID: wpr-55133
ABSTRACT
BACKGROUND:
It has been suggested that CDT is a potential biological marker in the Western countries to reflect the degree of past alcohol consumption. This study was performed to compare CDT, AST (aspartate transaminase), ALT (alanine transaminase), and GGT (gamma- glutamyl transferase) as a biological marker reflecting drinking amounts in Korean patients.METHODS:
The 25 males with moderate drinking(21 drinks/week) were studied for the relationships between their weekly drinking amount and the blood levels of CDT, AST, ALT, and GGT.RESULTS:
Only CDT was significantly correlated (P=0.001) with weekly drinking amount among heavy drinkers, while both CDT (P=0.029) and GGT (P=0.000) were significantly correlated in moderate drinkers. Stepwise multiple regression revealed that GGT had R2 of 49.1% in moderate drinkers and CDT had R2 of 38.9% in heavy drinkers for the weekly drinking amount.CONCLUSION:
The results described above suggested that CDT can be a potential biological marker for the purpose of quantitative monitoring the drinking behavior of heavy drinkers in Korea.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Consumo de Bebidas Alcoólicas
/
Transferrina
/
Biomarcadores
/
Ingestão de Líquidos
/
Comportamento de Ingestão de Líquido
/
Coreia (Geográfico)
Limite:
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Journal of the Korean Academy of Family Medicine
Ano de publicação:
2005
Tipo de documento:
Artigo
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