CONCEPT OF ALTERED FRACTIONATION SCHEDULES AND ITS APPLICATION IN THE TREATMENT OF NASOPHARYNGEAL,ESOPHAGEAL AND LUNG CANCER / 中华放射肿瘤学杂志

ABSTRACT

6hrs, followed by concomitant boost to a total dose of 74 Gy within 6 weeks. In lung cancer, the program was 1.15～1.25 Gy per fraction, two fractions per day for a total dose of 70 Gy with overall treatment time about 6 to 7 weeks. Esophageal cancer, conventional fractionation was given to total dose about 41 Gy followed by a boost for an additional 28 Gy by 1.5 Gy per fraction twice daily with overall treatment time about 6.3 weeks.Our preliminary treatment data showed that the local tumor control rates were higher in these study groups than the conventional groups and the acute reactions were increased as expected but tolerable. The main points of altered fractionation radiation schedules are also discussed.