The effects of DNA ploidy measurement on pathologic diagnosis of limbus epithelial neoplasms / 眼科

ABSTRACT

An apparatus of true color medical photometric analysis, a quantitative pathologic technique, was adopted to measure DNA ploidy content in 51 cases with limbus epithelial neoplasm. According to the DNA pattern, the cells in the neoplasm were divided into 4 types diploid (2C), tri-to tetraploid (3-4C), pentaploid (5C) and≥5C. In the lesion of epithelial hyperplasia, 2C-4C ceils accounted for 88.59%, and≥5C cells, 11.41%. In atypical hyperplasia, 2C-4C cells accounted for 58.62% and ≥5C cells, 41.38%. In the cases of carcinoma in situ and squamous cell carcinoma, 2C-4C cells accounted for 21.11% and 21.69%, and ≥5C cells, 78.89% and 78.31% respectively. These data were analyzed between each two groups by x~2 test (P