Protective effect of anisodaminum on light-induced rat retinopathy/ / 眼科

ABSTRACT

Acute intermittent visible fluorescent light was used as an experimental light source (18175?300lux, 1 hour dark: 1 hour light, 3 cycles). After light exposure, the myeloperoxidase activity (MDA) levels increased in rat retina, and the retinal structure and blood-retinal barrier were damaged. When 2 doses of anisodaminum (10 mg/Kg) were given 12 hours and just before light exposure, MDA levels lowered and the retinal structure was protected.