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The expression of TGF ? receptor Ⅰ and apoptosis in gastric carcinoma and precancerous lesions / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine ; (12)2001.
Artigo em Chinês | WPRIM | ID: wpr-552044
ABSTRACT
Objective To investigate the relationship between the expression of TGF ? receptor Ⅰ(RⅠ)and apoptosis in gastric carcinoma and precancerous lesions,and their effects in the development of gastric carcinoma.Methods The expressions of TGF ?RⅠ in 103 cases,including CSG(30 cases),IM(30 cases),Dys(18 cases)and GAC(25 cases)were detected by immunohistochemical techniques(SP),apoptosis cells were examined by terminal deoxynucleotidyl transferase(TdT) mediated dUTP nick end labelling(TUNEL).Results Both the expressions of TGF ?RⅠ and apoptosis indexes(AIpercentage of TUNEL positive cells)showed negative correlation with the degree of gastric mucosa lesions from CSG,IM,Dys to GAC(r=-0^7272,P

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Practical Internal Medicine Ano de publicação: 2001 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Practical Internal Medicine Ano de publicação: 2001 Tipo de documento: Artigo