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The Effect of Topical Dapiprazole on Phenylephrine and Tropicamide-induced Mydriasis
Journal of the Korean Ophthalmological Society ; : 1269-1274, 1993.
Artigo em Coreano | WPRIM | ID: wpr-55214
ABSTRACT
In order to evaluate the effect of topical dapiprazole, an alpha-adrenergic receptor blocker, in reversing mydrisis by 1% tropicamide and 2.5% phenylephrine, we studied 89 subjects. 0.5% dapiprazole in one eye of each subject after full dilatation of both pupils. The pupillary diameter was calibrated, and thereafter statistical analysis was performed with student paired t-test. Thirty minutes after instillation of dapiprazole, there was a highly significant difference of the decreasing rate in pupil size between the dapiprazole treated eyes and the control eyes(p<0.001). The time for complete reversal of mydriasis was also at least 4 hours shorter in the dapiprazole treated eyes than the control eyes(p<0.006). This study suggests that 0.5% dapiprazole is effective in reversing mydriasis caused by 1% tropicamide and 2.5% phenylephrine, and also effective in making the eyes comfortable in a shorter time.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Fenilefrina / Tropicamida / Midríase / Pupila / Dilatação Limite: Humanos Idioma: Coreano Revista: Journal of the Korean Ophthalmological Society Ano de publicação: 1993 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Fenilefrina / Tropicamida / Midríase / Pupila / Dilatação Limite: Humanos Idioma: Coreano Revista: Journal of the Korean Ophthalmological Society Ano de publicação: 1993 Tipo de documento: Artigo