ANALYSIS OF PLATELET ACTIVATION AND ITS CLINICAL SIGNIFICANCE IN OLDER HYPERTENSIVE PATIENTS / 解放军医学杂志
Medical Journal of Chinese People's Liberation Army
;
(12)1981.
Artigo
em Chinês
| WPRIM
| ID: wpr-552875
ABSTRACT
To investigate the changes of activated platelet marker and its significance in older hypertensive patients, glycoprotein Ⅱb/Ⅲa(PAC 1)and P selectin(CD62P) were used as molecular markers for activated platelets,which were analyzed by flow cytometric 3 color immunofluorescence. The results showed that PAC 1 expression on platelet membrane surface in older hypertensive patients was higher than that in healthy individuals and was not related with mean blood pressure.However, the expression of CD62P on platelets membrane surface did not differ in the two groups.These results suggest that PAC 1 may be regarded as a sensitive and specific molecular marker for activated platelets. Platelet activation occurrs in older hypertensive patients, and is of great importance for the antiplatelet therapy in hypertensive patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Medical Journal of Chinese People's Liberation Army
Ano de publicação:
1981
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS