STUDY ON EXPRESSION OF VEGF mRNA IN PULMONARY TISSUES OF TAIL-SUSPENDED RATS DURING SIMULATED WEIGHTLESSNESS / 解放军医学杂志

ABSTRACT

To investigate the changes of vascular endothelial growth factor mRNA (VEGFmRNA) in pulmonary tissues of tail suspended rats during simulated weightlessness,the experiments were conducted on 40 Spragno Dawley male rats,divided into 4 groupssuspended for 7d,control of 7d and suspended for 21d,control of 21d.Tail suspension(-30?) was used as weightlessness simulation.The condition of VEGFmRNA in pulmonary tissues was examined by hybridization in situ. The results showed that the level of VEGFmRNA in pulmonary tissues of 7d tail suspended rats increased significantly( P