THE EFFECT OF LOCAL APPLICATION OF BFGF AND SUCRALFATE COMBINED WITH CTE ON VIABILITY AND STRETCH-BACK OF EXPANDED SKIN FLAP IN A PIG MODEL / 解放军医学杂志

ABSTRACT

To investigate the effect of bFGF and sucralfate on the improvement of the quality of expanded skin flap, white piglets were employed to establish a continuous tissue expansion model. They were randomly divided into 3 groups group 1 both bFGF and sucralfate were injected; group 2 both bFGF and normal saline was injected; and group 3(the control group)only normal saline was injected. Three days after completion of the expansion ,normal and expanded skin flaps were created at random to assess flap viability and stretch back .The results showed that the flap survival length in group 1 was significantly larger than that of the control group and normal random flap( P