Relationship between paraoxonase 2 A148G polymorphism and diabetic nephropathy / 中华肾脏病杂志
Chinese Journal of Nephrology
;
(12)1997.
Artigo
em Chinês
| WPRIM
| ID: wpr-553410
ABSTRACT
Objective To determine whether the paraoxonase2 (PON2) gene A148G polymorphism is associated with the pathogenesis of nephropathy in type 2 diabetes mellitus patients (DN) . Methods PON2 genotype distribution and allele frequency were examined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) . Serum immune reactive insulin (IRI) and C-peptide (C-P) concentrations were measured by radioimmunity. Results GG genotype and G allele frequency were higher in DN group than that in simple type 2 diabetes mellitus group (x2 =4. 26 P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Nephrology
Ano de publicação:
1997
Tipo de documento:
Artigo
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