Mirodenafil for the Treatment of Erectile Dysfunction: A Systematic Review of the Literature
The World Journal of Men's Health
;
: 18-27, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-55353
ABSTRACT
Phosphodiesterase type 5 (PDE5) inhibitors are the most commonly used treatment for erectile dysfunction (ED). Since the launch of sildenafil, several drugs-including mirodenafil, sildenafil citrate (sildenafil), tadalafil, vardenafil HCL (vardenafil), udenafil, and avanafil-have become available. Mirodenafil is a newly developed pyrrolopyrimidinone compound, which is a potent, reversible, and selective oral PDE5 inhibitor. Mirodenafil was launched in Korea in 2007, and an orally disintegrating film of mirodenafil was developed in 2011 for benefitting patients having difficulty in swallowing tablets. This study aimed to review the pharmacokinetic characteristic profile of mirodenafil and report evidence on its efficacy in the case of ED. In addition, we reviewed randomized controlled studies of mirodenafil's daily administration and efficacy for lower urinary tract symptoms.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Comprimidos
/
Resultado do Tratamento
/
Ácido Cítrico
/
Deglutição
/
Inibidores da Fosfodiesterase 5
/
Sintomas do Trato Urinário Inferior
/
Citrato de Sildenafila
/
Dicloridrato de Vardenafila
/
Tadalafila
/
Disfunção Erétil
Tipo de estudo:
Ensaio Clínico Controlado
/
Revisões Sistemáticas Avaliadas
Limite:
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
The World Journal of Men's Health
Ano de publicação:
2014
Tipo de documento:
Artigo
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