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Effect and mechanism of emodin on intestinal movement / 中国药理学通报
Article em Zh | WPRIM | ID: wpr-554585
Biblioteca responsável: WPRO
ABSTRACT
AIM To examine the effect and mechanism of emodin on intestinal movement of constipation model. METHODS The movement of charcoal powder and the absorption of D-xylose into serum were observed. The electrical p otential difference(PD) related to Na + and glucose transport was measured across the wall of rev erted intestinal sacs. RESULTS Emodin 0 1, 0 2 g?kg -1 incr eased markedly the rate of charcoal powder moving and inhibited the absorption of D-xylose into serum. Emodin 0 2, 0 4, 0 8 and 1 6 g?L -1 decreased PD when ther e was glucose. However, emodin had little effect when glucose was free. CONCLUSION Emodin promotes intestinal movement and this effect is related to Na +,K +-ATPase.
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Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Pharmacological Bulletin Ano de publicação: 2003 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Pharmacological Bulletin Ano de publicação: 2003 Tipo de documento: Article