Inhibitor of apoptosis proteins(IAP):Novel anticancer targets / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12)1987.
Artigo
em Chinês
| WPRIM
| ID: wpr-554735
ABSTRACT
An endogenous suppressor of apoptosis, the inhibitor of apoptosis proteins(IAP) plays a key role in the occurrence and progression of cancer. In recent years cancer researches have been focused on gene-specific inhibitors with IAP as the target, so as to seek gene therapeutic strategies of less toxicity and higher efficiency. As members of IAP family, survivin and livin are over-expressed in tumors. Meanwhile, Smac can directly inhibit IAP. These findings suggest a promising alternative strategy for developing novel anticancer therapies.-
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmacological Bulletin
Ano de publicação:
1987
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS