Changes of gastric emptying and small intestinal transit time in patients with diabetes mellitus / 中国实用内科杂志

ABSTRACT

Objective To assess gastric emptying of mixed meal in patients with diabetes mellitus (DM) and small intestinal transit of solid meal.Methods Gastric emptying of solid and liquid food,and small intestinal transit time of solid food were measured in patients with DM by a dual isotopic technique.Anterior and posterior images were recorded by SPECT.Results The average time of 50% gastric and proximal gastric emptying of solid food and the maximal counting time of distal gastric solid food were much longer in patients than those in controls.About 40%-44% patients exceeded normal range.The change of the average time of delay phase was not significant,but 48% patients exceeded normal range;the change of gastric emptying of liquid food was not significant.But in patients,the small intestinal transit time of solid food was significantly longer than that of healthy controls.Conclusion The average transit time of solid meal in DM patients is longer,but their gastric emptying of liquid food is normal.