The Postoperative Antiemetic Effect of Midazolam in Patients Undergoing Appendectomy / 대한마취과학회지
Korean Journal of Anesthesiology
; : 1095-1100, 1999.
Article
em Ko
| WPRIM
| ID: wpr-55498
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND: Postoperative nausea and vomiting are common postoperative complaints. The purpose of this study was to assess the effect of preoperative midazolam on vomiting after appendectomy. METHODS: Sixty patients, aged 10 64 yr, undergoing emergency appendectomy were randomly allocated to receive midazolam 30, 50, 75 microgram/kg or placebo after induction of anesthesia. Anesthesia consisted of 67% nitrous oxide, 33% oxygen and propofol infusion 6 10 mg/kg/h. Postoperative vomiting was checked by the recovery room nurse at 1 h after operation and we examined the incidence of postoperative vomiting at 24 h after operation. RESULTS: Midazolam reduced the overall incidence of vomiting, especially in the midazolam 50 and 75 microgram/kg groups, completely abolishing vomiting (P< 0.05). However, in the midazolam 75 microgram/kg group, there was a delay in eye opening time (P< 0.05). CONCLUSIONS: Preoperative injections of midazolam 30 or 50 microgram/kg were useful to prevent postoperative vomiting in patients undergoing appendectomy without delayed recovery.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Oxigênio
/
Apendicectomia
/
Sala de Recuperação
/
Vômito
/
Midazolam
/
Propofol
/
Incidência
/
Náusea e Vômito Pós-Operatórios
/
Emergências
/
Anestesia
Tipo de estudo:
Clinical_trials
/
Incidence_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Anesthesiology
Ano de publicação:
1999
Tipo de documento:
Article