Diagnostic of Cushing's syndrome

ABSTRACT

From the year 1989 to December 1994, 59 patients with Cushing syndrome (12 males, 47 females aged 15-46) were investigated. Clinical symptoms: central obesis, round face, weakness, high blood pressure, cracked skin, mental disorder, acnea, hirsulism. Laboratory examinations: high level of urine 17OHCS, cortisol secretion increasing in 8 and 20 o’clock and loss of secretion. Morphological examinations: X-ray radiography of hypophysal hole, ultrasound of surrenal gland, CT scan of hypophysal hole. Causes: 79.7% is Cushing disease, 11.8% adenoma od surrenal gland, 8.5% surrenal cancer