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Roles of histone acetyltransferases and deacetylases in the process of cell proliferation,differentiation and tumorogenesis / 医学研究生学报
Journal of Medical Postgraduates ; (12): 249-251,254, 2001.
Artigo em Chinês | WPRIM | ID: wpr-556285
ABSTRACT
Acetylation of lysine residues of core histone N-terminal domains has been found correlatively associated with transcriptional activation in eukaryotes. Recent studies showed that some transcriptional regulators with histone acetyltransferase(HAT) and deacetylase(HDAC) activities may play a causative role in regulating gene expression. The link between tumorigenic processes and misregulated or mistargeted HAT and HDAC activities has been reported.
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Journal of Medical Postgraduates Ano de publicação: 2001 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Journal of Medical Postgraduates Ano de publicação: 2001 Tipo de documento: Artigo