Therapeutic drug monitoring of vancomycin in a patient with Duchenne muscular dystrophy (DMD): A case report
Translational and Clinical Pharmacology
;
: 124-126, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-55670
ABSTRACT
Vancomycin is a widely used glycopeptide antibiotic that requires therapeutic drug monitoring (TDM) owing to its narrow therapeutic window. It is primarily eliminated by renal excretion; thus, estimating the renal function of a patient is vital in the TDM of vancomycin. In patients with Duchenne muscular dystrophy (DMD), it is difficult to estimate the glomerular filtration rate using the serum creatinine level owing to the pathophysiological nature of the disease. Here, we report a case of a patient in whom TDM of vancomycin was performed, and explore the appropriate methods for evaluating renal function in patients with DMD based on serum levels of creatinine and cystatin C.
Texto completo:
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Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Vancomicina
/
Monitoramento de Medicamentos
/
Distrofia Muscular de Duchenne
/
Creatinina
/
Cistatina C
/
Eliminação Renal
/
Taxa de Filtração Glomerular
Limite:
Humanos
Idioma:
Inglês
Revista:
Translational and Clinical Pharmacology
Ano de publicação:
2016
Tipo de documento:
Artigo
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