Changes in gastrointestinal circulation during the operation of orthotopic liver transplantation / 解放军医学杂志

ABSTRACT

Objective To investigate the changes in gastrointestinal circulation during the operation of orthotopic liver transplantation. Methods In 15 patients undergoing orthotopic liver transplantation, PgCO2 and PaCO2 were determined and the values of Pg-aCO_2 and pHi were calculated at the time points as follows pre-operation (T0), 30min before anhepatic phase (T1), 30min of anhepatic phase (T2), and 5min (T3), 30min (T4) and 90min (T5) after reperfusion of the transplanted liver, and at the end of the operation(T6). Results Compared with that of pre-operation, PgCO2 and Pg-aCO2 increased significantly at the following time points 30min before anhepatic phase, 30min of anhepatic phase, as well as 5min and 30min after reperfusion of the transplanted liver (P0.05). The values of pHi decreased significantly at 30min before anhepatic phase, 30min of anhepatic phase, and 5min and 30min in neohepatic phase (P