Study of comparison of optic nerve between big cupped disc and early glaucoma / 眼科

ABSTRACT

Objective To investigate the sensitivity of Heidelberg Retina Tomography (HRT-Ⅱ)parameters on the early optic nerve change of glaucoma head. Design Cross-sectional study. Participants Twenty-one patients (36 eyes) with big cupped disc(C/ D≥0.7) and twenty-seven patients (31 eyes) with early glaucoma (C/D≥0.7, MD≤3dB) were studied. Methods All patients underwent visual field and HRT-Ⅱ examination to get parameters of optic nerve head. T test was used to compare the parameters of optic disc between big cupped disc and early glaucoma. Main Outcome Measures HRT Ⅱ parameters included disc area, cup area, rim area, cup volume, rim volume, C/D area ratio, mean cup depth, maximum cup depth, cup shape measure, height variation contour, mean RNFL thickness and RNFL cross sectional area. Results Statistics analysis with T test (t=2.247-3.714, P=0.000-0.028) showed there were significant differences of rim area, rim volume, mean retinal nerve fiber layer thickness, sectional area of retinal nerve fiber layer between big cupped disc and early glaucoma. Conclusions We can pay attention to those parameters with HRT- Ⅱ to distinguish patients with big cupped disc and early glaucoma.