Effect of truncal vagotomy on biliary dynamics in dogs / 第三军医大学学报

ABSTRACT

Objective To explore the effect of truncal vagotomy on biliary dynamics in dogs.Methods After fasted for 18 h, 12 adult mongrel dogs underwent bilateral truncal vagotomy at the diaphragmatic level and pyloroplasty in the experiment group,and only pyloroplasty in the control group.All dogs were performed ultrasonograph to determine the size of the common bile duct(CBD) and sphincter of Oddi manometry(SOM) to detect biliary dynamics at postoperative 8 weeks,then the bile was collected from gallbladder for further analysis.Results In the experiment group,the CBD pressure,inner diameter of CBD,and SO basal pressure(SOBP) increased significantly,and sediments were found in the bile of all dogs,but SO amplitude(SOAP),frequency and duration of SO phasic contraction did not change.Conclusion Bilateral truncal vagotomy at the diaphragmatic level leads to significant increase of SOBP,resulting in a great change of biliary dynamics.