Levels of interleukin-6 and CRP in patients with chronic obstructive pulmonary disease and its significance / 中国实用内科杂志

ABSTRACT

Objective To investigate IL-6 and CRP levels,and their relationship with airflow obstruction、frequency of exacerbation in patients with COPD.Methods From Feb.2004 to Jul.2004,sputum and serum specimens were obtained from 54 patients with stable COPD and 10 age-matched healthy controls.The concentrations of sputum IL-6 and serum IL-6 were measured by ELISA.The concentrations of sputum CRP and serum CRP were measured by transmissive heterometric titration.Results (1)Sputum IL-6 levels in COPD patients of all stages were higher than those in controls(P