Studies on the chemical constituents of Bidens bipinnata L / 第二军医大学学报

ABSTRACT

Objective:To investigate the bioactive chemical constituents in Bidens bipinnata L.for treatment of diabetes.Methods: Extraction was done with 80% EtOH;isolation and purification were carried out on silica gel,C_(18) silica gel column,and Sephadex-LH20 column;and the chemical structures of the products were identified by physicochemical properties and spectral analysis.Results: Nine compounds were obtained from Bidens bipinnata L.and their chemical structures were identified as: quercitin(Ⅰ),hyperoside(Ⅱ),quercitin-7-O-rhamnopyranoside(Ⅲ),6,7,3'4'-tetrahydroxy aurone(Ⅳ),4,5-di-O-caffeoyl quinic acid(Ⅴ),stigmasterol 3-O-glucopyranoside(Ⅵ),ethyl 3,4-dihydroxybenzoate(Ⅶ),okanin(Ⅷ),and luteolin(Ⅸ).Conclusion: Except for okanin and hyperoside,the rest 7 compounds are isolated from the plant for the first time.