Observation on cerebrovascular hemodynamic index in experimental atherosclerotic rabbits / 国际生物医学工程杂志

ABSTRACT

Objective To observe the changes of cerebrovascular hemodynamic index(CVHI) in atherosclerotic rabbits. Methods Twenty male New Zealand rabbits were randomly divided into two group Twelve were atherosclerosis model (AS) group and eight were control group. Atherosclerosis model group were fed with high fat diet and control group were fed with ordinary diet. At 12th week, CVHI were measured in the common carotid artery with spectral analysis and the compliance of carotid was observed. Results In the AS group, the carotid artery maximal velocity (vmax) and minimal velocity (vmin) were significantly decreased (P