Effects of ozone-stress on E-cadherin expression in human bronchial epithelial cells / 中国临床药理学与治疗学
Chinese Journal of Clinical Pharmacology and Therapeutics
;
(12)2004.
Artigo
em Chinês
| WPRIM
| ID: wpr-559954
ABSTRACT
AIM:
To explore the expression of E-cadherin(E-cd) in the human bronchial epithelial cells(HBECs) and their role in the damage and injury of the airway.METHODS:
The E-cd protein expression and the Ecd mRNA of HBECs were determined by immunocytochemistry analysisand RT-PTR analysis,respectively.RESULTS:
Ozone-stress caused a decrease in the HBECs membrane E-cd expression and an increase the cytoplasmic E-cd expression(P(0.05)).CONCLUSION:
E-cd is distributed on HBECs.O_3-stress decreases the membrane E-cd expression but increases the cytoplamic E-cd expression.The change of E-cd expression may mediate HBECs injuries induced by O_3-stress.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Clinical Pharmacology and Therapeutics
Ano de publicação:
2004
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS