Expression of human telomerase reverse transcriptase hTERT,Ki-67 and p27~(kip1) in pheochromocytoma and their significance / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
;
(12)2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-560344
ABSTRACT
Objective To investigate the expression of human telomerase reverse transcriptase(hTERT),Ki-67 and p27~(kip1) in pheochromocytoma and paraganglioma,and to evaluate whether the expression of hTERT,Ki-67 and p27~(kip1) could serve as diagnostic markers for predicting the biological behaviour of these tumours.Methods Expression of hTERT,Ki-67 and p27~(kip1) was determined by immunohistochemistry in 45 pheochromocytomas/paragangliomas(31 benign,7 suspected malignant and 7 malignant)and 9 normal adrenal medulla samples.Results The hTERT was expressed in 5/7 malignant tumors,5/7 suspected malignant tumours and 3/31 benign tumours.Malignant and suspected malignant tumors expressed more hTERT(P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Practical Internal Medicine
Ano de publicação:
2006
Tipo de documento:
Artigo
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